CVE-2026-100843

HIGH
Published September 27, 2026

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the...

Full CISO analysis pending enrichment.

How severe is it?

CVSS 3.1
7.8 / 10
EPSS
N/A
Exploitation Status
No known exploitation
Sophistication
N/A

What is the attack surface?

AV AC PR UI S C I A
AV Local
AC Low
PR None
UI Required
S Unchanged
C High
I High
A High

What should I do?

No patch available

Monitor for updates. Consider compensating controls or temporary mitigations.

Which compliance frameworks are affected?

Compliance analysis pending. Sign in for full compliance mapping when available.

Frequently Asked Questions

What is CVE-2026-100843?

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Is CVE-2026-100843 actively exploited?

No confirmed active exploitation of CVE-2026-100843 has been reported, but organizations should still patch proactively.

How to fix CVE-2026-100843?

No patch is currently available. Monitor vendor advisories for updates.

What is the CVSS score for CVE-2026-100843?

CVE-2026-100843 has a CVSS v3.1 base score of 7.8 (HIGH).

What are the technical details?

Original Advisory

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Weaknesses (CWE)

CWE-502 — Deserialization of Untrusted Data: The product deserializes untrusted data without sufficiently ensuring that the resulting data will be valid.

  • [Architecture and Design, Implementation] If available, use the signing/sealing features of the programming language to assure that deserialized data has not been tainted. For example, a hash-based message authentication code (HMAC) could be used to ensure that data has not been modified.
  • [Implementation] When deserializing data, populate a new object rather than just deserializing. The result is that the data flows through safe input validation and that the functions are safe.

Source: MITRE CWE corpus.

CVSS Vector

CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H

Timeline

Published
September 27, 2026
Last Modified
September 27, 2026
First Seen
September 27, 2026